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PubMed · 2838138

A readable and space-efficient DNA sequence representation: application to caulimoviral DNAs.

U Melcher
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Abstract

A new representation of nucleotide sequence information has been devised to allow the clear presentation of large amounts of sequence information in a limited amount of space. Nucleotide sequences of DNA are represented by squares in three vertically aligned positions for each nucleotide. The squares represent, from top to bottom: a purine, a guanine or cytosine and a pyrimidine. The representation provides a simultaneous representation of both strands of double-stranded DNA and can be easily scanned visually for a variety of sequence features. Biologically important features of the DNA sequence near the origin of SV40 replication are easily recognized. The representation was also used to identify possibly base-paired stems in caulimoviral transcripts that may be of significance for viral replication.

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Base SequenceComputer GraphicsDNADNA, ViralMolecular Sequence DataMosaic VirusesNucleic Acid ConformationSequence Homology, Nucleic AcidSimian virus 40SoftwareJournal ArticleResearch Support, Non-U.S. Gov't

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BibTeXRIS

U Melcher. 1988. A readable and space-efficient DNA sequence representation: application to caulimoviral DNAs.. https://doi.org/10.1093/bioinformatics%2F4.1.93

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