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PubMed · 2840921

[Nephroblastoma with symptomatic neuronal differentiation].

J P Saint-André·M C Chapeau·F Pein
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Abstract

We report the anatomoclinical analysis of a child with a renal tumor: the preoperative diagnosis was neuroblastoma, because of elevated dopamine urinary excretion and positive MIBG scintigraphy. The histopathological and immunohistochemical analysis revealed a prominent neural differentiation in a multicystic nephroblastoma. This observation recalls the Masson's proposed neuroectodermal histogenesis of Wilms tumor; however the currently accepted metanephrogenic blastematous origin is not reconsidered. This is the first case of nephroblastoma with a neural differentiation detectable otherwise from by pathological analysis.

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Cell DifferentiationChild, PreschoolHumansImmunohistochemistryKidney NeoplasmsNeuronsWilms TumorCase ReportsEnglish AbstractJournal Article

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J P Saint-André, M C Chapeau, F Pein. 1988. [Nephroblastoma with symptomatic neuronal differentiation].. https://pubmed.ncbi.nlm.nih.gov/2840921/

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