Cellular requirements for cutaneous sensitivity elicitation.

I Aoki

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PubMed · 2856185

Cellular requirements for cutaneous sensitivity elicitation.

I Aoki

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Abstract

The role of glass-adherent cells in cutaneous sensitivity (CS) elicitation has been analyzed in this study. CS responses have been revealed to be mediated by at least two distinct subsets of genetically restricted T cells: I-restricted 'DTH-like' T cells and K/D-restricted 'CTL-like' T cells. Both T-cell responses require I-A-positive glass-adherent cell populations, which lack T-cell markers, to manifest their activities. The role of the adherent cells is different in the 'DTH-like' responses and the 'CTL-like' responses. The disparities between the present results and previous contentions are discussed in this paper.

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Animals Antigen-Presenting Cells Cell Separation Glass H-2 Antigens Histocompatibility Antigens Class II Hypersensitivity, Delayed Immunization, Passive Macrophages Mice Mice, Inbred C57BL T-Lymphocytes Journal Article Research Support, Non-U.S. Gov't

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I Aoki. 1985. Cellular requirements for cutaneous sensitivity elicitation.. https://pubmed.ncbi.nlm.nih.gov/2856185/

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