[Benzodiazepines and sleep].

M Ansseau

PubMed · 2865871

[Benzodiazepines and sleep].

Abstract

Benzodiazepines currently represent the most widely prescribed family of hypnotic drugs. They possess obvious advantages: actual hypnotic efficacy, at least with short-term use, low toxicity, and excellent tolerance. However, several side effects need to be mentioned: besides morning drowsiness (which represents the untoward continuation of their sedative properties), anterograde amnesia, increase of daytime anxiety, and rebound insomnia. Moreover, benzodiazepines significantly modify several sleep parameters: they decrease slow wave sleep and delay the first period of REM sleep. Any hypnotic benzodiazepine should only be prescribed in case of actual need and after exclusion of non-pharmacologic means. The "softest" agent, at the lowest dose, and during the shortest period should always be preferred.

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Anti-Anxiety Agents Belgium Benzodiazepines Europe Humans Hypnotics and Sedatives Sleep Initiation and Maintenance Disorders Sleep Wake Disorders United States Comparative Study English Abstract Journal Article

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M Ansseau. [Benzodiazepines and sleep].. https://pubmed.ncbi.nlm.nih.gov/2865871/

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