PubMed · 2905283
Postmenopausal endometrial patterns and serum estradiol concentrations.
Abstract
Eighty postmenopausal women were subjected to endometrial biopsy. Inadequate biopsy was recorded in 30 cases. In the remaining cases (n = 50) the correlation between endometrial patterns and serum estradiol (E2) was performed. These cases were presenting with uterine bleeding (n = 38) or minor gynecological symptoms (n = 12). Proliferative endometrium was the predominant endometrial pattern whereas endometrial malignancy was only present in 15.8% of the bleeding cases. Serum E2 was significantly elevated in cases having malignant endometrium or adenomatous hyperplasia compared to cases having other endometrial patterns. Serum E2 measurement is recommended as a simple screening test for the detection of postmenopausal endometrial hyperplasia and/or malignancy.
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A A Ismail, M Ramadan, A Soliman, A Rahmy, A Rizk. 1988. Postmenopausal endometrial patterns and serum estradiol concentrations.. https://doi.org/10.1016/0020-7292(88)90096-3
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