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The circulatory response to specific ventilatory patterns using a tidal volume ventilator.

S Lindahl·J Kugelberg·L Okmian
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Abstract

The circulatory response to different ventilatory patterns during artificial ventilation was examined in 17 sternotomized piglets. A constant CO2-tension level was maintained in all investigations by reference to analyses of the end-tidal infra-red CO2 fraction and arterial CO2-tension. The greatest variation in mean values for end-tidal CO2-tension was 0.2 kPa. Total compliance and lung compliance were lower at a ventilator volume/pressure quotient of 20 compared to those at 80 ml/kPa, and at f = 30 compared to f = 11 cycles/min. Higher cardiac output, lower pulmonary vascular resistance and systemic vascular resistance were measured at f = 11 (inspiration 20%) than at f = 30 (inspiration 50%). An increase in inspiration time by about 100% at the lower ventilatory frequency (f = 11) resulted in a significant but uncompensated decrease in cardiac output and stroke volume. These results demonstrate the value of a rapid insufflation in order to give longer expiration time per minute for the benefit of the venous return and cardiac output.

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AnimalsCardiac OutputHemodynamicsLung ComplianceLung Volume MeasurementsPartial PressurePressureRespiration, ArtificialStroke VolumeSwineTidal VolumeTracheaVascular ResistanceVentilators, MechanicalJournal Article

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BibTeXRIS

S Lindahl, J Kugelberg, L Okmian. 1979. The circulatory response to specific ventilatory patterns using a tidal volume ventilator.. https://doi.org/10.1111/j.1399-6576.1979.tb01464.x

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