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Antioxidants and platelets.

J T Salonen
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Abstract

It is postulated that antioxidants reduce platelet activity by the stimulation of prostacyclin synthetase by scavenging synthesis-inhibiting peroxides. The experimental and clinical evidence supporting this theory is inconclusive. Clinical trials suggest that vitamin E reduced platelet aggregability. Nonexperimentally, a strong association has been observed between low serum selenium concentration and increased platelet aggregability. These findings suggest that antioxidants have an important role in the regulation of platelet function.

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AntioxidantsAscorbic AcidBlood PlateletsHumansPlatelet AggregationVitamin EJournal Article

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J T Salonen. 1989. Antioxidants and platelets.. https://doi.org/10.3109/07853898909149183

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