Reference values for peripheral blood lymphocytes from Aotus lemurinus ssp. griseimembra (owl monkey).

C W Caldwell; J E Mrema; H M Taylor; T J Green

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Reference values for peripheral blood lymphocytes from Aotus lemurinus ssp. griseimembra (owl monkey).

C W Caldwell·J E Mrema·H M Taylor·T J Green

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Abstract

The reactivities of several monoclonal antibodies that define human lymphocyte cell-surface antigens have been tested with peripheral blood lymphocytes of Aotus lemurinus ssp. griseimembra. Based on reactivity patterns in humans, reactive MoAb were identified that mark pan-T, helper/inducer, suppressor/cytotoxic, pan-B, and natural killer cells. Reference values of these subsets in Aotus are presented. These MoAb should provide a useful tool for further phenotypic and functional dissection of the immune system in this simian model of human disease.

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Animals Antibodies, Monoclonal Aotus trivirgatus B-Lymphocytes Cebidae Flow Cytometry Fluorescent Antibody Technique Killer Cells, Natural Leukocyte Count Lymphocytes Reference Values T-Lymphocytes T-Lymphocytes, Helper-Inducer T-Lymphocytes, Regulatory Journal Article Research Support, U.S. Gov't, Non-P.H.S.

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C W Caldwell, J E Mrema, H M Taylor, T J Green. 1987. Reference values for peripheral blood lymphocytes from Aotus lemurinus ssp. griseimembra (owl monkey).. https://pubmed.ncbi.nlm.nih.gov/2957504/

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