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PubMed · 2977658

[Decrease of HCG level after conservative laparoscopic treatment of extra-uterine pregnancy].

J L Pouly·G Mage·H Manhes·F Gachon·G Gaillard·M A Bruhat
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Abstract

HCG levels have been studied in 76 patients following laparoscopic treatment using laparotomy. This shows that early detection of treatment failure is possible of ectopic pregnancy. The decrease of HCG was the same as after conservative treatment from the third or fifth post-operative day onwards. The authors report a scheme for the post-operative follow-up after laparoscopic treatment of ectopic pregnancy based on the rate of HCG decrease.

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Chorionic GonadotropinFemaleHumansLaparoscopyPregnancyPregnancy, EctopicEnglish AbstractJournal Article

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J L Pouly, G Mage, H Manhes, F Gachon, G Gaillard, M A Bruhat. 1988. [Decrease of HCG level after conservative laparoscopic treatment of extra-uterine pregnancy].. https://pubmed.ncbi.nlm.nih.gov/2977658/

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Elevated second trimester maternal serum beta-HCG concentrations and subsequent adverse pregnancy outcome.

Previous studies have found an association between elevated second trimester maternal serum alpha-fetoprotein (MS-AFP), in the absence of fetal anomalies, and adverse pregnancy outcome. We studied the association between elevated second trimester maternal serum beta-HCG, now also routinely measured by prenatal screening programs, and adverse pregnancy outcome by reviewing retrospectively the pregnancy outcomes among women with markedly elevated midtrimester beta-HCG in our prenatal screening program. Seven (0.23%) of 3,000 consecutively screened women had a serum beta-HCG above 5 MOM. Four (57%) of these 7 women had an adverse pregnancy outcome including severe preeclampsia (n = 2), abruptio placentae (n = 1), or preterm labor (n = 1). A concurrently elevated MS-AFP was found in only one of these 4 patients. Elevated mid-trimester maternal serum beta-HCG may be an independent risk factor for subsequent adverse pregnancy outcomes.

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