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PubMed · 2980581

Genetic brain malformations recapitulate phylogeny.

M Sarwar
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Abstract

It is generally difficult to establish whether a congenital brain malformation has a genetic basis or is due to other factors. A thesis has been developed, that brain malformations with a genetic basis recapitulate phylogeny. In order to validate this thesis a retrospective CT investigation of brain dysmorphology was carried out in 50 cases of dysgenesis of the corpus callosum, 20 cases of the holoprosencephaly complex, 25 cases of Dandy-Walker malformation, and 50 cases of miscellaneous brain anomalies. This group was compared with 100 neonates with brain damage from acquired causes. The results strongly suggest that a brain malformation that recapitulates phylogeny is very likely to be based on genetic aberration.

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AnimalsBrainHumansInfant, NewbornPhylogenyJournal Article

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M Sarwar. 1986. Genetic brain malformations recapitulate phylogeny.. https://pubmed.ncbi.nlm.nih.gov/2980581/

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