The missense errors in protein can be controlled by selective synonymous codon usage at the level of transcription.

A K Konopka; V Brendel

doi:10.1016/s0300-9084(85)80265-0

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The missense errors in protein can be controlled by selective synonymous codon usage at the level of transcription.

A K Konopka·V Brendel

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Abstract

In the cases of the 6-fold degenerate residues and the stop signal, selective codon usage at the level of transcription can account for a 10-20% variation in their mistranslation rate. For all other residues, the mistranslation rate is dependent upon the degree of degeneracy only, but not upon the pattern of synonymous codon usage.

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Animals Aspartate Carbamoyltransferase Bacterial Proteins Base Sequence Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing)Codon Dihydroorotase Mathematics Multienzyme Complexes Proteins RNA, Messenger Transcription, Genetic Viral Proteins Journal Article Research Support, Non-U.S. Gov't

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A K Konopka, V Brendel. 1985. The missense errors in protein can be controlled by selective synonymous codon usage at the level of transcription.. https://doi.org/10.1016/s0300-9084(85)80265-0

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