In vitro cell transformations induced by 31 MeV protons.

D Bettega; P Calzolari; P Pollara; L T Lombardi

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PubMed · 3001815

In vitro cell transformations induced by 31 MeV protons.

D Bettega·P Calzolari·P Pollara·L T Lombardi

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Abstract

Experimental data are presented on the frequencies of transformations in C3H10T1/2 cells exposed to 31 MeV protons (LET = 1.83 +/- 0.02 keV/mum in tissue) in a dose interval between 0.25 and 7.0 Gy. The transformation frequency per surviving cell curve showed a marked change in slope over the dose range used. At higher doses, above about 2 Gy, it steepened very sharply in comparison with the lower dose range. If fitted to a power of the dose, the power in the higher range was about five times that in the lower range.

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Animals Cell Line Cell Survival Cell Transformation, Neoplastic Dose-Response Relationship, Radiation Mice Protons Journal Article Research Support, Non-U.S. Gov't

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D Bettega, P Calzolari, P Pollara, L T Lombardi. 1985. In vitro cell transformations induced by 31 MeV protons.. https://pubmed.ncbi.nlm.nih.gov/3001815/

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