Complete cDNA sequence for rabbit muscle glycogen phosphorylase.

K Nakano; P K Hwang; R J Fletterick

doi:10.1016/0014-5793(86)80829-8

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Complete cDNA sequence for rabbit muscle glycogen phosphorylase.

K Nakano·P K Hwang·R J Fletterick

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Abstract

The cDNA for the nearly full-length rabbit muscle glycogen phosphorylase mRNA has been isolated and sequenced. The cDNA is rich in G and C nucleotides. This feature is especially striking at the 3rd position of codons, where 86% of the 843 amino acid codons terminate with G or C. Methionine, presumably the initiation residue, is found at position-1, suggesting that the removal of only a single methionine residue precedes the amino-terminal acetylation at serine. Eight differences between the deduced amino acid sequence and the previously determined protein sequence are discussed.

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Amino Acid Sequence Animals Base Sequence Cloning, Molecular DNA DNA Restriction Enzymes Isoleucine Muscles Phosphorylases Protein Biosynthesis Rabbits Journal Article Research Support, U.S. Gov't, P.H.S.

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K Nakano, P K Hwang, R J Fletterick. 1986-08-18. Complete cDNA sequence for rabbit muscle glycogen phosphorylase.. https://doi.org/10.1016/0014-5793(86)80829-8

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