[Cardiovascular function in liver cirrhosis].

K Lenz

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PubMed · 3035300

[Cardiovascular function in liver cirrhosis].

K Lenz

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Abstract

The hemodynamic pattern in patients with cirrhotic liver disease shows a hypercirculatory state, with elevated cardiac output and decreased systemic vascular resistance. Studies on myocardial function gave different results, whereby non hepatic factors as a cause of myocardial dysfunction are reasonable. Decreased vascular resistance is predominantly caused by an accumulation of vasodilating substances. A dysfunction of vasoconstricting systems could not be found. A previously discussed interference of the sympathetic nervous system could not be confirmed in further studies. This hypercirculatory state may be catastrophic in hypovolemic states, as in acute bleeding, or concomitant septic hyperdynamic states, because the initial compensatory mechanisms are not available any more.

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Blood Pressure Cardiac Output Cardiovascular System Heart Failure Heart Rate Heart Ventricles Hemodynamics Humans Liver Cirrhosis Liver Cirrhosis, Alcoholic Receptors, Adrenergic, alpha Renal Circulation Vascular Resistance English Abstract Journal Article

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K Lenz. 1987. [Cardiovascular function in liver cirrhosis].. https://pubmed.ncbi.nlm.nih.gov/3035300/

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