Motor performance in hyperactive children treated with imipramine.

C T Gualtieri; R W Evans

doi:10.2466/pms.1988.66.3.763

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Motor performance in hyperactive children treated with imipramine.

C T Gualtieri·R W Evans

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Abstract

The effects of the tricyclic antidepressant imipramine were evaluated in a study of 9 children with Attention Deficit-Hyperactivity Disorder. The study was double-blind, placebo-controlled, with three drug conditions, low, medium, and high doses. The focus was on neuropsychological drug effects. Imipramine exerted negative dose-response effects on motor performance (motor speed, motor pursuit), while it improved hyperactive behavior and attention and raised the heart rate slightly.

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Arousal Attention Attention Deficit Disorder with Hyperactivity Child Clinical Trials as Topic Dose-Response Relationship, Drug Double-Blind Method Female Humans Imipramine Male Motor Activity Psychomotor Performance Random Allocation Clinical Trial Controlled Clinical Trial Journal Article

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C T Gualtieri, R W Evans. 1988. Motor performance in hyperactive children treated with imipramine.. https://doi.org/10.2466/pms.1988.66.3.763

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