Nucleotide sequence of streptococcal pyrogenic exotoxin type C.

S C Goshorn; P M Schlievert

doi:10.1128/iai.56.9.2518-2520.1988

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Nucleotide sequence of streptococcal pyrogenic exotoxin type C.

S C Goshorn·P M Schlievert

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Abstract

The nucleotide sequence of the gene speC, encoding streptococcal pyrogenic exotoxin type C (SPE C), was determined. The gene encoded a mature protein of 208 amino acids, with a calculated molecular weight of 24,354. The mature amino acid sequence of SPE C was analyzed for homology with the amino acid sequences of streptococcal pyrogenic exotoxin type A, the staphylococcal enterotoxins, and toxic shock syndrome toxin-1. Of these, SPE C shared the greatest amount of homology with streptococcal exotoxin type A.

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Amino Acid Sequence Bacterial Proteins Base Sequence Cloning, Molecular Exotoxins Membrane Proteins Molecular Sequence Data Sequence Homology, Nucleic Acid Streptococcus pyogenes Comparative Study Journal Article Research Support, U.S. Gov't, P.H.S.

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S C Goshorn, P M Schlievert. 1988. Nucleotide sequence of streptococcal pyrogenic exotoxin type C.. https://doi.org/10.1128/iai.56.9.2518-2520.1988

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