PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 3050327

[The amyloidoses].

L Carvajal Huerta·E Uraga·F Tama·I García·T Pico
View original source ↗Export metadata ↓

Abstract

There are many clinical types of amyloidosis, as many as chemical types of amyloid substance would be its substratum. This clinic-chemical plurality permits us to talk about the amyloidosis. This article is specially guided to those amyloidosis that present cutaneous damages during its clinical course. They are the immunocytic amyloidosis and the keratinocytic amyloidosis.

Explore related subjects

AmyloidosisFemaleHumansMaleMiddle AgedSkin PigmentationCase ReportsEnglish AbstractJournal ArticleReview

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

L Carvajal Huerta, E Uraga, F Tama, I García, T Pico. 1988. [The amyloidoses].. https://pubmed.ncbi.nlm.nih.gov/3050327/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2007

Schistosoma-induced amyloidosis in hamsters is gender-dependent.

BACKGROUND: A high serum level of female protein (FP), found to be a constituent of Syrian hamster amyloid was associated with enhanced amyloidosis. In this work, we studied the sex-limited factors in the induction of amyloidosis in Syrian hamsters infected with either Schistosoma mansoni or S. hematobium cercariae. METHODS: Hamsters were infected with different species of schistosome cercariae and sacrificed after different time periods of infection. Kidney and liver specimens were processed in paraffin, stained with Congo-red and examined by ordinary light and polarized light microscopy. RESULTS: Statistical analysis showed a significant difference in intensity of kidney and liver amyloid deposits (P<0.002 & <0.007 respectively) between females and male hamsters with extensive deposits in the former. Amyloid deposits were correlated significantly to the duration of infection (P<0.001) than the load of worm recovered. CONCLUSION: From this study, we conclude that, in hamster model, Schistosoma-induced amyloidosis is enhanced in females than male hamsters. This may be due to the high serum level of FP that is normally detected in females. As an experimental model for schistosomal nephropathy, we recommend to use male hamsters instead of females to minimize the effect of amyloid deposits, which may mask other pathological changes associated with schistosomal infection.

Amyloidosis↗