[Primary hyperparathyroidism. Recent physiopathological data].

Abstract

Recent advances in the physiology of the parathyroid hormone permit a better demonstration of the mechanisms of inappropriate hypersecretion which characterizes hyperparathyroidism, even through the etiology of primary forms still remains unknown. There have been also some progress achieved understanding and evaluating the impact od hypersecretion on target organs, especially bone and kidney. Some studies give an indication of the therapeutic modalities which would enable to reduce the excess of secretion, to counteract the effect of the hormone on its receptor sites or finally limit its consequences on osteopenia.