Molecular Koch's postulates applied to microbial pathogenicity.

S Falkow

doi:10.1093/cid/10.supplement_2.s274

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Molecular Koch's postulates applied to microbial pathogenicity.

S Falkow

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Abstract

Microbial genetics and molecular cloning now permit us to routinely isolate specific genes from a variety of microbial pathogens. Obviously not all genes from pathogenic microorganisms play a role in pathogenicity or virulence. Just as Koch's postulates were formulated to identify the causal relationship between an organism and a specific disease, the notion is presented here that a form of molecular Koch's postulates is needed when examining the potential role of genes and their products in the pathogenesis of infection and disease.

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Animals Bacteria Cloning, Molecular Genes, Bacterial Humans Mutation Virulence Journal Article Review

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S Falkow. Molecular Koch's postulates applied to microbial pathogenicity.. https://doi.org/10.1093/cid%2F10.supplement_2.s274

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