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Autoimmunity in demyelinating diseases.

B H Waksman
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Abstract

Demyelinative diseases of the CNS and peripheral nervous system can be distinguished on the basis of primary mediation by antibody or T lymphocytes (or failure of the T-cell-mediated response) and on the basis of chronicity. The principal mechanisms are autoimmunization to myelin antigens after actual immunization with tissue or infection with cross-reactive viruses or, alternatively, persistent infection of the nervous system (viral or spirochetal) with an associated immune response to the pathogen.

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AnimalsAntigen-Antibody ComplexAntigensAutoimmune DiseasesDemyelinating DiseasesHumansImmunity, CellularMultiple SclerosisNervous SystemT-LymphocytesVirus DiseasesJournal ArticleReview

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BibTeXRIS

B H Waksman. 1988. Autoimmunity in demyelinating diseases.. https://doi.org/10.1111/j.1749-6632.1988.tb27047.x

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