Metabolic profile testing.

Abstract

Metabolic profiles have been used in efforts to predict periparturient problems and fertility, to diagnose metabolic disease, and to assess nutritional status. Results have been varied. Until knowledge and technology provide improved blood constituent panels, the metabolic profile should not be the first step in the diagnostic process. Rather, such profiles should follow an assessment of management practices and an evaluation of diet. However, these profiles may help to confirm the diagnosis, to convince dairy farmers that management changes are desirable, or to monitor improvement in herd animals. At this point, their major contribution has been to increase our understanding of the factors contributing to changes in blood constituent concentrations, which, in turn, has led to more efficient means of diagnosis. Except in cases of gross mismanagement, these profiles do not offer a "quick fix." In many of the reported cases in which diagnosis of herd problems was attributed to the metabolic profile, the clinician should have been able to identify the problem before the profile was conducted. Profiles are to be recommended when the cause of an existing problem is still not identified or resolved after a complete evaluation. The profile may aid in identifying a factor that has been overlooked. Profiles are not for clinicians who do not have an interest in upgrading their understanding of the factors involved, or who do not have a source of knowledgeable advice.