PubMed · 3063730
Physiologic pharmacokinetic modeling.
Abstract
Although physiologic modeling has not gained the widespread acceptance that was originally projected, it may serve as the basis for future PK/PD modeling approaches. In addition, with more effort applied to developing in vitro and animal-to-human predictions, physiologic modeling may assume a higher position in the pharmacokinetic modeling hierarchy.
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W A Colburn. 1988. Physiologic pharmacokinetic modeling.. https://doi.org/10.1002/j.1552-4604.1988.tb03199.x
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