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Sibs with the polyasplenia developmental field defect.

H V Toriello·N Kokx·J V Higgins·R Hofman·D F Waterman
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Abstract

We report on two brothers each with absent spleen, multiple cardiac defects, and varying degrees of situs inversus. One brother also had omphalocele; the other also had annular pancreas. These findings are consistent with a diagnosis of polyasplenia, a complex developmental field defect affecting visceral and cardiac situs, with associated spleen and heart defects. We also discuss familial cases from a developmental field perspective.

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Abnormalities, MultipleHeart Defects, CongenitalHumansInfant, NewbornMaleSpleenCase ReportsJournal Article

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H V Toriello, N Kokx, J V Higgins, R Hofman, D F Waterman. 1986. Sibs with the polyasplenia developmental field defect.. https://doi.org/10.1002/ajmg.1320250606

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