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PubMed · 3154747

Cautery dissection in levator surgery.

R P Carroll
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Abstract

This report describes a new technique that facilitates dissection of tissue planes and essentially eliminates intraoperative bleeding, two of the most frequently encountered problems during levator surgery. The described technique has been used in more than 450 consecutive eyelids with congenital and acquired ptosis requiring levator surgery. Disinsertion or dehiscence of the aponeurosis was found in less than 5% of the cases of involutional ptosis.

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BlepharoptosisCauteryEyelidsHumansOculomotor MusclesSurgical Procedures, OperativeTendonsJournal ArticleResearch Support, Non-U.S. Gov't

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R P Carroll. 1988. Cautery dissection in levator surgery.. https://doi.org/10.1097/00002341-198804040-00009

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Oculopharyngeal muscular dystrophy (OPMD) is a late-onset muscle disorder characterized by progressive dysphagia and bilateral ptosis. Mutations in the polyadenylate binding protein nuclear 1 (PABPN1) gene have been found to cause OPMD. The typical mutation is a stable trinucleotide repeat expansion in the first exon of the PABPN1 gene, in which (GCG)(6) is the normal repeat length. We investigated a Korean patient with OPMD and identified a novel mutation: a heterozygous insertion of a 9-bp sequence [(GCG)(GCA)(GCA); c.27_28insGCGGCAGCA] instead of the (GCG) repeat expansion, resulting in an in-frame insertion of three alanines (p.A10insAAA). To the best of our knowledge, this is the first report of a genetically confirmed case of OPMD in Korea.

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