PubMed · 3177595
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E Kenyon. 1988. RGP lens binding.. https://pubmed.ncbi.nlm.nih.gov/3177595/
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We compared the relative value of biomicroscopy, pachometry, esthesiometry, and corneal oxygen flux measurements for the detection of corneal hypoxia in myopic patients wearing hydrogel extended wear lenses. Measurements were standardized by relating the change in each parameter to its test-retest reliability. After 3 months of extended wear the greatest change occurred in biomicroscopic signs (microcysts and vacuoles, fluorescein staining, inferior conjunctival hyperemia) and in stromal edema measured with pachometry. These four signs were poorly correlated to each other (Pearson's r < 0.3), indicating that none could be considered redundant. Stromal striae, endothelial edema (blebs), esthesiometry, and corneal oxygen flux measurements showed relatively little change during the period of lens wear.
The rigid gas-permeable (RGP) extended-wear lens offers a unique alternative to the hydrogel extended-wear lens as well as to refractive surgery. In suitable patients it can provide almost maintenance-free visual correction for a wide variety of refractive errors. With prudent patient selection, use of high-permeability RGP materials, sound lens design and fitting principles, and conservative follow-up procedures, RGP extended-wear lenses can have success rates exceeding those of either hydrogel extended-wear lenses or refractive surgery, with fewer complications. The complications that do occur are often predictable after a short period of daily wear, and the remainder can often be managed with small changes to lens design.
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