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A SAS procedure for fitting data to binomial and Poisson probability distributions.

J Lee
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J Lee. 1988. A SAS procedure for fitting data to binomial and Poisson probability distributions.. https://doi.org/10.1177/101053958800200412

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Incidence patterns and genetic validation of primary glaucoma subtypes among 1 million adults in China and the UK.

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Neonatal outcomes following antenatal corticosteroid administration before planned caesarean birth at late preterm or early term (36-38 weeks' gestation): a retrospective cohort study.

OBJECTIVE: To investigate the benefits and harms associated with antenatal corticosteroids (ACS) prior to planned caesarean birth at late preterm or early term. DESIGN: Retrospective cohort study. SETTING: South Australia, Australia, 2005-2018. PATIENTS: Women with singleton pregnancies undergoing planned caesarean birth between 36+0 and 38+6 weeks' gestation. METHODS: We used routinely collected electronic maternity and neonatal data. Adjusted risk differences (aRD) with 95% CIs were calculated for neonatal and maternal outcomes. OUTCOME MEASURES: Neonatal outcomes included respiratory distress requiring oxygen, hypoglycaemia requiring glucose, neonatal unit (NNU) admission and prolonged NNU admission (≥48 hours). RESULTS: Among the cohort of 4049 women, the proportion receiving ACS was 54.8%, 48.4% and 5.6% at 36, 37 and 38 completed weeks' gestation, respectively. ACS administration was associated with a significant reduction in respiratory distress across all gestations, with the greatest reduction seen at 36 weeks' gestation (aRD -12.5%; 95% CI -21.4% to -3.6%). At 38 weeks' gestation, ACS administration was associated with an increased risk of neonatal hypoglycaemia (aRD 5.7%; 95% CI 1.1% to 10.2%), NNU admission (aRD 5.4%; 95% CI 0.1% to 10.7%) and prolonged NNU admission (aRD 4.6%; 95% CI 0.2% to 8.9%). CONCLUSIONS: ACS administration prior to late preterm and early term planned caesarean birth was associated with reduced risk of respiratory distress. The net benefit of ACS administration before planned caesarean birth remains unclear; however, there was evidence of potential neonatal harm when birth occurred after 37 weeks' gestation.

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The full bibliography of Ernst Ludwig Wynder.

The chronology of lifetime publications authored and/or co-authored by Dr. Ernst L. Wynder spans a rich assortment of topics relating to the etiology and prevention of chronic diseases. Dr. Wynder's interdisciplinary approach to research in cancer and heart disease embraces the disciplines of epidemiology, biology, pathology, chemistry, biochemistry, tobacco sciences, and nutrition as well as health behavior, and health education. His works reflect his attention to diverse subjects from methodology in scientific endeavors, to mechanisms in carcinogenesis, brain development, alternative medicine, principles of disease prevention, history of medicine, and societal issues, as well as philosophy, and religion. In 1972 Dr. Wynder created the journal Preventive Medicine as an international forum for the exchange of ideas that address the promotion of health and prevention of disease in our time. Many of his ideas were developed and nurtured in the symposia and workshops the Journal has published.

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