Chymopapain--past and present, future?

L T Ford

PubMed · 319933

Chymopapain--past and present, future?

Abstract

Clinical experience with Chymopapain casts doubts upon the reported results of the limited double blind studies done mainly by surgeons and their residents, relatively inexperienced in the disc injection technique. Chymopapain is a useful drug when used properly for lumbar disc disease and has the potential of eliminating three-fourths of lumbar disc surgery. Chymopapain should have been released by the FDA on a Phase IV basis. In the mean-time the drug is available in Canada and England but not in the U.S.

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Animals Cervical Vertebrae Chymopapain Clinical Trials as Topic Endopeptidases Humans Intervertebral Disc Displacement Lumbar Vertebrae Male Middle Aged Nervous System Diseases Spinal Diseases United States United States Food and Drug Administration Case Reports Clinical Trial Journal Article Review

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L T Ford. Chymopapain--past and present, future?. https://pubmed.ncbi.nlm.nih.gov/319933/

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