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PubMed · 320607

Interaction between thiamine hydrochloride and lipoic acid.

H O Ammar·H A Salama
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Abstract

An interaction between thiamine hydrochloride and DL-alpha-lipoic acid in aqueous solution was depicted. Evidence is presented through spectrophotometric as well as vapour pressure measurements to show that thiamine hydrochloride and DL-alpha-lipoic acid form a single 1:1 complex. The stability constant and the molar extinction coefficient of the complex (at 244 nm) were determined at 25 degrees C and found to be 3.1-10(4) and 970, respectively. Vapour pressure measurements at 60 degrees C reveal that more or less complete dissociation of the complete takes place at this temperature.

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SolutionsSpectrophotometry, UltravioletTemperatureThiamineThioctic AcidVolatilizationJournal Article

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H O Ammar, H A Salama. 1977. Interaction between thiamine hydrochloride and lipoic acid.. https://pubmed.ncbi.nlm.nih.gov/320607/

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