Memory deficit in passive-avoidance learning in bulbectomized Long-Evans hooded rats.

B M Thorne; J S Rowles

doi:10.1016/0031-9384(88)90035-2

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Memory deficit in passive-avoidance learning in bulbectomized Long-Evans hooded rats.

B M Thorne·J S Rowles

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Abstract

Male and female Long-Evans hooded rats were subjected to either olfactory bulb damage or control surgery. Olfactory bulb removal resulted in increased mouse killing, increased irritability to handling, and increased open-field activity. In acquisition trials on a modified passive-avoidance apparatus, control animals habituated rapidly to the apparatus, while OB rats showed little evidence for habituation. All controls showed 24-hour retention of shock on the last acquisition trial, while OB rats showed the typical retention deficit, despite being given a behavioral alternative to withholding a response. The P-A deficit in OB rats appears to be a learning/memory deficit, not the result of heightened activity.

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Aggression Animals Arousal Avoidance Learning Body Weight Electroshock Female Male Memory Mental Recall Motor Activity Olfactory Bulb Orientation Rats Rats, Inbred Strains Journal Article Research Support, U.S. Gov't, Non-P.H.S.

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B M Thorne, J S Rowles. 1988. Memory deficit in passive-avoidance learning in bulbectomized Long-Evans hooded rats.. https://doi.org/10.1016/0031-9384(88)90035-2

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