Proto-oncogenes II.

P Rosen

doi:10.1016/0306-9877(88)90009-6

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Proto-oncogenes II.

P Rosen

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Abstract

In reviewing recent literature on activated proto-oncogenes including retroviral infection (without oncogene), translocation and inherited childhood cancer, I have come to the conclusion that activated proto-oncogenes are not involved in development of tumors. There is one exception in which a translocated proto-myc leads to transformation. That is the case of the trangenic mouse embryo where faulty development occurs.

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Animals Gene Amplification Humans Models, Genetic Neoplasms Proto-Oncogenes Retroviridae Translocation, Genetic Journal Article

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P Rosen. 1988. Proto-oncogenes II.. https://doi.org/10.1016/0306-9877(88)90009-6

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