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PubMed · 3226903

Sequence-defined dimer block synthesis from unprotected nucleoside.

T Shimidzu·H Ozaki·S Yamoto·S Maikuma·K Honda·K Yamana
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Abstract

mediates to synthesize the oligodeoxynucleotides have been synthesize otected nucleoside using morpholinophosphorditetrazolide. From these sequence-defined oligodeoxynucleotides were also synthesized. The gen is composed of following steps; a) reaction of 5'-O-protected nucleo orpholinophosphorditetrazolide (phosphitilation), b) reaction of the nucleoside phosphoramidite with the second nucleoside (condensation), ueous oxidation with t-BuOOH (oxidation). RE 1/hlp F2/cmt F3/ext F4/can F5/nxt F6/ins F7/up F8/dwn F9/fin

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Indicators and ReagentsNucleosidesNucleotidesOligodeoxyribonucleotidesStructure-Activity RelationshipJournal Article

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BibTeXRIS

T Shimidzu, H Ozaki, S Yamoto, S Maikuma, K Honda, K Yamana. 1988. Sequence-defined dimer block synthesis from unprotected nucleoside.. https://pubmed.ncbi.nlm.nih.gov/3226903/

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