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PubMed · 3247682

[Selection for a decrease in metastatic potential in a cell population of transplantable rat rhabdomyosarcoma RA-2].

I V Guzhova·Iu B Vakhtin
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Abstract

The method of individual cloning was used for checking the reduction of metastatic potential (MP) in cell population of highly malignant rhabdomyosarcoma RA-2. In the course of 15 selection cycles MP was lowered by 10-15 times. These data enabled us to consider the MP value as a quantitative character of malignant cells with low heritability (the mean value of realized heritability coefficient is equal to 0.18).

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AnimalsClone CellsLung NeoplasmsNeoplasm MetastasisNeoplasm TransplantationRatsRhabdomyosarcomaSelection, GeneticTumor Cells, CulturedEnglish AbstractJournal Article

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I V Guzhova, Iu B Vakhtin. 1988. [Selection for a decrease in metastatic potential in a cell population of transplantable rat rhabdomyosarcoma RA-2].. https://pubmed.ncbi.nlm.nih.gov/3247682/

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