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PubMed · 326195

Lupus band test.

E W Monroe
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Abstract

The lupus band test (LBT) is a direct immunofluorescent technique for demonstrating a band of localized immunoglobulins at the dermal-epidermal junction in the skin of patients with lupus erythematosus (LE). Studies have shown immunoglobulins and complement at the dermal-epidermal junction in systemic (involved and uninvolved skin) and in discoid (involved skin only) LE. It is essential that the appropriate skin site be selected for biopsy; ie, involved or uninvolved skin, light-exposed or light-protected skin. The proper location of the biopsy site is determined by whether the LBT is intended for diagnostic or prognostic purposes. From a diagnostic standpoint, the LBT is a very sensitive and specific test for LE. In addition, this procedure has considerable value as a prognostic test for a patient with an established diagnosis of LE.

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BiopsyCollagen DiseasesDiagnosis, DifferentialFluorescent Antibody TechniqueHumansImmunoglobulin AImmunoglobulin GImmunoglobulin MImmunoglobulinsLupus Erythematosus, DiscoidLupus Erythematosus, SystemicPrognosisJournal Article

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E W Monroe. 1977. Lupus band test.. https://pubmed.ncbi.nlm.nih.gov/326195/

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