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FLP recombinase is an enzyme.

C A Gates·M M Cox
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Abstract

The FLP protein of the yeast 2-microns plasmid catalyzes intermolecular site-specific recombination with a turnover number of approximately equal to 0.12 min-1 (per FLP monomer) for relaxed DNA substrates. Under conditions that enhance its stability, the protein can be used in catalytic rather than stoichiometric amounts. The reaction rate exhibits a strong dependence on FLP protein concentration even when the protein is present in excess relative to available recombination sites.

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Base SequenceDNA NucleotidyltransferasesDNA, FungalFungal ProteinsPlasmidsRecombination, GeneticSaccharomyces cerevisiaeJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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C A Gates, M M Cox. 1988. FLP recombinase is an enzyme.. https://doi.org/10.1073/pnas.85.13.4628

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