Laboratory tests for total and allergen-specific immunoglobulin E.

J K Weltman

doi:10.2500/108854188778994986

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Laboratory tests for total and allergen-specific immunoglobulin E.

J K Weltman

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Abstract

The principles of measurement of IgE by enzyme-immunoassay are given. A Bayesian approach is taken for the clinical interpretation of serum total IgE. Application of Bayes' Theorem to serum total IgE can significantly influence the probability of a clinical diagnosis of allergy. There is a correlation between allergen-specific IgE measured by enzyme-immunoassay, by radioallergosorbent test and by skin tests for immediate hypersensitivity. However, there is a need to standardize the reagents used for allergy skin testing, as well as the reagents and methods used for the laboratory measurement of allergen-specific IgE.

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Allergens Bayes Theorem Humans Hypersensitivity, Immediate Immunoenzyme Techniques Immunoglobulin E Immunosorbent Techniques Radioallergosorbent Test Skin Tests Comparative Study Journal Article

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J K Weltman. Laboratory tests for total and allergen-specific immunoglobulin E.. https://doi.org/10.2500/108854188778994986

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