PubMed HealthSearch

PubMed · 329477

A hydrostatic device for tissue dehydration.

Abstract

A simple device for mixing water and organic solvents can be easily constructed to dehydrate tissue for electron microscopy. The device utilizes hydrostatic leveling between a reservoir and a mixing chamber to produce a continuously increasing concentration of dehydrating solvent. The rate of dehydration may be regulated by geometry and/or outflow rate. A prototype model is described which compactly incorporates the solvent reservoirs and a tissue tray that can accommodate ten tissue specimens in stainless steel mesh baskets. The device can be fabricated cheaply and replaces manual dehydration.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

D Goldfarb, K Miyai, J Hegenauer. 1977. A hydrostatic device for tissue dehydration.. https://doi.org/10.3109/10520297709116770

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

The development of a microwave fluid-bed processor. II. Drying performance and physical characteristics of typical pharmaceutical granulations.

Four typical pharmaceutical granulations were used to measure the enhanced drying performance of a laboratory-sized microwave fluid-bed processor, the design and construction of which were presented in Part I of this work (preceding paper). Results demonstrate improvements in observed drying rates by as much as sixfold depending upon the granulation type and drying conditions. At a low inlet temperature (30 degrees C), drying was achieved with microwave power inputs of 100-125 W/liter of working capacity, whereas similar targeted moisture levels were unattainable using conventional fluid-bed drying. Microwave energy available for heating and drying was 68 to 86% of the total microwave energy inputted.

Desiccation