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Recognition of a polymorphic monocyte antigen.

G R Menzel·M Rose
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Abstract

138 sera from renal transplant recipients were screened for the presence of monocyte-specific antibodies. Most of the sera contained antibodies against monocytes, T- and/or B-lymphocytes. One serum was identified which defined a monocyte-specific antigen, MOLI. This serum was investigated in intensive population and family studies for the estimation of the formal genetic criteria of this 'new' monocyte antigen. A gene frequency of 0.0614 was obtained by population analysis. Family investigations conveyed the information that the gene coding for MOLI was transmitted in linkage with HLA genes. A positive linkage disequilibrium of MOLI and HLA-B17 was found.

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AntibodiesAntigensB-LymphocytesGene FrequencyGenetic LinkageHumansKidney TransplantationMonocytesPedigreeT-LymphocytesJournal Article

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BibTeXRIS

G R Menzel, M Rose. 1987. Recognition of a polymorphic monocyte antigen.. https://doi.org/10.1111/j.1423-0410.1987.tb04947.x

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