PubMed · 3334411
Kinetic-effect models and their applications.
Abstract
This article focuses on mathematical models that analyze the time course of drug effects in humans. Any such model, whether parametric or nonparametric, is termed a kinetic-effect model (KEM). These models serve to describe (interpolation) and to predict (extrapolation) the effect-time profile. KEMs are applicable to many problems in pharmaceutics, pharmacology, and clinical pharmacology.
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J Grevel. 1987. Kinetic-effect models and their applications.. https://doi.org/10.1023/a%3A1016402616081
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