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Trophoblast membrane infusion for unexplained recurrent miscarriage.

P M Johnson·K V Chia·C A Hart·H B Griffith·W J Francis
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Abstract

A novel protocol is described which has been developed for immunotherapy in unexplained recurrent miscarriage. This is based on a single intravenous infusion with isolated placental trophoblast plasma membrane vesicle preparations. Clinical experience gained with this approach is described. A total of 16/21 (76%) patients who subsequently had pregnancies have now achieved a live birth or are currently pregnant at greater than 28 weeks gestation.

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Abortion, HabitualAdultAntigens, SurfaceCell MembraneFemaleHumansImmunizationPregnancyTrophoblastsJournal ArticleResearch Support, Non-U.S. Gov't

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P M Johnson, K V Chia, C A Hart, H B Griffith, W J Francis. 1988. Trophoblast membrane infusion for unexplained recurrent miscarriage.. https://doi.org/10.1111/j.1471-0528.1988.tb06603.x

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