Polymerized actin in lymphoid cells: functional interpretation.

P J Philip; B Mely-Goubert

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PubMed · 3382752

Polymerized actin in lymphoid cells: functional interpretation.

P J Philip·B Mely-Goubert

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Abstract

Nitrobenzoxadiazol (NBD) phallacidin, an active fluorescent derivative of the actin-binding mushroom toxin phallacidin provides a convenient actin-specific fluorescent label for cellular cytoskeleton structures. Topographical fluorescent microscopy images of lymphoid cells obtained with NBD-phallacidin staining reveal that the major feature of the cellular cytoskeleton characterized by actin are mainly associated with cell membrane, a pattern that correlates strikingly with their DNAse 1 inhibition. Such actin pools may thus be involved in a membrane-associated protein network controlling membrane viscoplastic deformation and cell motility.

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Actins Amanitins Cell Membrane Fibroblasts Flow Cytometry Fluorescent Dyes Humans Lymphocytes Polymers Journal Article

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P J Philip, B Mely-Goubert. 1988. Polymerized actin in lymphoid cells: functional interpretation.. https://pubmed.ncbi.nlm.nih.gov/3382752/

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