Eosinophilic enteritis with perforation.

H S Walia; T K Abraham; H K Walia

Home/Archive/PubMed

PubMed · 3390775

Eosinophilic enteritis with perforation.

H S Walia·T K Abraham·H K Walia

View original source ↗Export metadata ↓

Abstract

A case of eosinophilic granuloma of the gastrointestinal tract with free perforation is described. The authors believe this is the first such case to be published. The patient, a 60-year-old woman, had no history of allergy. At laparotomy, 100 ml of pus was aspirated. A 42-cm section of small bowel, containing multiple punched-out ulcers, was excised. The mucosa and submucosa of the operative specimen were edematous; there was a moderate inflammatory infiltrate containing numerous eosinophils and neutrophils. The lesion appeared to represent a local reaction to some antigen with resultant eosinophilic infiltration.

Explore related subjects

Enteritis Eosinophilia Female Humans Intestinal Perforation Jejunal Diseases Middle Aged Case Reports Journal Article

Keep this discovery

Explore connections, maps & timelines

BibTeX RIS

H S Walia, T K Abraham, H K Walia. 1988. Eosinophilic enteritis with perforation.. https://pubmed.ncbi.nlm.nih.gov/3390775/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2006

Histamine, mast cells, and the enteric nervous system in the irritable bowel syndrome, enteritis, and food allergies.

Explore the source record for details and available documents.

Enteritis↗

PubMed2005

Enteritis cystica profunda presenting as ileoileal intussusception in a child: report of a case.

We report the case of a 3-month-old male infant with small bowel intussusception caused by enteritis cystica profunda (ECP). The baby was admitted because he was refusing to feed, and was passing "red-currant jelly"-like stools. A palpable mass was identified, and abdominal ultrasonography showed a mass with a lumen and lumen appearance. We performed laparotomy and resected the segment of bowel containing the mass. The resected segment had enteritis cystica profunda, which was considered to have precipitated the intussusception. A review of the English medical literature revealed only three other cases of children with similar symptoms in the last 30 years.

Enteritis↗

PubMed2005

Enteropathogenic Escherichia coli: unravelling pathogenesis.

Enteropathogenic Escherichia coli (EPEC) is a gram-negative bacterial pathogen that adheres to intestinal epithelial cells, causing diarrhoea. It constitutes a significant risk to human health and remains an important cause of infant mortality in developing countries. Although EPEC was the first E. coli strain to be implicated in human disease in the 1940s and 1950s, the mechanisms by which this pathogen induced diarrhoea remained a complete mystery throughout most of the 40 years since its description. It was only during the late 1980s that major advances were made in unravelling the mechanisms behind EPEC pathogenesis. Ever since, progress has been made at a stunning pace and there have been major breakthroughs in identifying the bacterial factors involved in attaching and effacing (A/E) lesion formation, host signal transduction pathways in response to EPEC infection and the genetic basis of EPEC pathogenesis. The rapid pace of discovery is a result of intensive research by investigators in this field and portends that EPEC will soon be among one of the most understood diarrhoea-causing infectious agents. This review aims to trace the progress of EPEC research since its existence was first reported by John Bray in 1945, highlighting the major findings that have revolutionised our understanding of EPEC pathogenesis.

Enteritis↗