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Replication termination for staphylococcal plasmids: plasmids pT181 and pC221 cross-react in the termination process.

S Iordanescu·S J Projan
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Abstract

We present data which indicate that (i) the origin of replication of plasmids pT181 and pC221 can also function as termination signals; (ii) termination of replication occurs when a round of replication initiated either by RepC at the pT181 origin or by RepD at the pC221 origin reaches either of these origins, proving that the two plasmids cross-react for termination of replication; and (iii) the replication initiated at the origin of another staphylococcal plasmid, pE194, does not terminate at the origin of pT181 or pC221, indicating the existence of a specific relationship between the initiation and termination of a replication event.

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Bacterial ProteinsBase SequenceCross ReactionsDNA ReplicationDNA, BacterialElectrophoresis, Agar GelGenetic VectorsMolecular Sequence DataPlasmidsStaphylococcus aureusVirus ReplicationJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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S Iordanescu, S J Projan. 1988. Replication termination for staphylococcal plasmids: plasmids pT181 and pC221 cross-react in the termination process.. https://doi.org/10.1128/jb.170.8.3427-3434.1988

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