PubMed HealthSearch

PubMed · 3464263

Schizophrenia: an information processing model.

Abstract

There is a wealth of literature associating schizophrenia with disorders of information processing and attention. This paper draws together knowledge from experimental cognitive psychology and examines how both research findings and the clinical manifestations of schizophrenia can be accommodated by an information processing paradigm. An attentional model of schizophrenia is proposed in which disorders in the perception of information are related to dysfunction at the level of preattentive processes. This is seen as one crucial difference between schizophrenia and bipolar disorder, both of which demonstrate failures of sensory gating and filter mechanisms in the acquisition and processing of inputs. Commonalities between the two disorders are thus addressed. Certain psychopathological phenomena in schizophrenia, particularly negative symptoms ('inhibition'), hallucinations and delusions, are seen as compensatory operations of a disordered information processing system. The model has heuristic value and is able to account for, and coherently organise, the variability which continues to confound research in schizophrenia.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

V Carr, J Wale. 1986. Schizophrenia: an information processing model.. https://doi.org/10.3109/00048678609161327

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Cardiovascular phase relationships to the cortical event-related potential of schizophrenic, depressed, and normal subjects.

Cardiovascular phase, especially diastole, influences attention and the event-related potential (ERP) of the right hemisphere of the brain. Depression and schizophrenia are characterized by attentional deficits, unique lateralization of brain function, and deviant phase relationships of biological oscillators. In the present study, the ERP was recorded during stimulation triggered by diastole and systole in control (n = 16), depressed (n = 16), and schizophrenic (n = 9) subjects. Fifty tones were presented and subjects were instructed to count them silently. Previous findings were supported of delayed latencies and increased amplitude in depressed patients and decreased amplitudes and delayed latencies in schizophrenics. An exaggerated effect of diastole on the ERP in the right hemisphere was observed in depressed patients, however, no cardiovascular effect on the ERP was apparent in schizophrenic patients. Results suggested that heart/brain networks are tightly coupled in normal controls, perhaps "overdriven" in depressed patients, and uncoupled in schizophrenics.

Arousal

Blood flow response to auditory stimulations in normal, mentally retarded, and autistic children: a preliminary transcranial Doppler ultrasonographic study of the middle cerebral arteries.

Using the noninvasive transcranial ultrasonic Doppler method, flow dynamics of the middle cerebral arteries were investigated in relation to auditory stimulations in 12 children with autistic behavior compared with 12 normal controls and 10 mentally retarded children. In normal children, auditory stimulation evoked lateralized modifications: blood flow increased and resistance index decreased on the left side; such modifications were not recorded on the right side. This pattern should indicate vasodilatation mechanisms induced by changes in the metabolism of the brain areas supplied by the left middle cerebral arteries (MCA). Although less asymmetrical, this pattern was also found in the mentally retarded children. Autistic children significantly differed from these two groups. They displayed a symmetric pattern of responses with a blood flow decrease and resistance-index increase on both sides; this could suggest abnormal metabolic mechanisms induced by auditory stimulation in autistic children and could be related to the previous hypothesis of impairment in the development of cerebral lateralization in autism. These preliminary results show that transcranial Doppler ultrasonography may be a valuable and practicable tool for the noninvasive study of evoked blood flow responses in psychopathology.

Arousal