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PubMed · 3495221

Centric fission consequences in man.

H Rivera·J M Cantú
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Abstract

The authors summarise the consequences of centric fission in man as follows: classical (monocentric) isochromosomes; usually either for p or q, exceptionally for both arms; stable telocentrics for either one or both arms; isochromosome for one arm, stable telocentric for the other; isochromosome for one arm concurring with translocation of the telocentric for the other; telocentric/isochromosome mosaicism for the same arm; stable telocentric for a part of one arm, the remaining of the chromosome forming a smaller element (obviously this rearrangement requires an additional break outside the centromere), and whole-arm translocations. These events are discussed in the light of current notions about centromere structure and function.

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H Rivera, J M Cantú. 1986. Centric fission consequences in man.. https://pubmed.ncbi.nlm.nih.gov/3495221/

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