PubMed · 3513639
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P P Weinstein. 1986. Filariasis: problems and challenges.. https://doi.org/10.4269/ajtmh.1986.35.221
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Studies on the occurrence of early symptoms of filariasis have been conducted in two transmigration Units in the valley of the Wae Apu river, Buru island, Maluku Province, Indonesia. In both Units, higher disease rates were found in areas, where there was a closer contact with positive natives, higher density of the vector mosquito, and higher infective rates in the mosquitoes.
A 1-year-old immunodeficient boy developed brawny edema of the left foot. Lymphoscintigraphy revealed no evidence of left inguinal activity following pedal injection of Tc-99m-Sn phosphate. Over the next two months, the patient developed lymphedema on the right and repeat scintigraphy demonstrated no movement of isotope from the dorsum of either foot. Subsequent studies identified microfilaria in a nocturnal blood smear, which were thought to represent Brugia beaveri acquired by mosquito transmission in Oklahoma.