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PubMed · 3515284

[Osteoid induction].

L Schweiberer·K Hallfeldt·H Mandelkow
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Abstract

Osteoinduction is a biological principle. The implantation of tissue with inductive properties results in the proliferation and differentiation of undifferentiated cells to cartilage and bone. This process, which is similar to a cascade-type mechanism, is controlled by a series of humoral and local growth factors. It was possible to isolate a number of macromolecular substances with osteoinductive, mitogenic, or chemotactic properties specifically from the extracellular bone matrix. A deeper understanding of the regulative mechanisms as well as the greater availability of growth factors may lead to new therapeutic approaches in bone surgery.

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AnimalsBone Morphogenetic ProteinsBone RegenerationBone TransplantationFreezingGrowth SubstancesHumansInsulin-Like Growth Factor IIOsteogenesisProteinsTissue PreservationEnglish AbstractJournal Article

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L Schweiberer, K Hallfeldt, H Mandelkow. 1986. [Osteoid induction].. https://pubmed.ncbi.nlm.nih.gov/3515284/

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