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PubMed · 3537416

Mood alterations and sleep.

R Rimon·M Fujita·N Takahata
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Abstract

We have reviewed literatures about neurobiological aspect of mood disorders in the light of abnormalities of REM sleep. A shortened REM latency is a consistent finding in depressed patients and may be considered a biological marker for depression. Most depressed patients with shortened REM latency also show non-suppression on dexamethasone-suppression test (DST). The commonly used antidepressant drugs cause a significant reduction in REM sleep. Patients with abnormal DST show a better response to sleep deprivation than those with normal DST. Recent studies indicated that borderline patients, primary dysthymic patients and obsessive-compulsive patients (OCD) have shortened REM latency. Farthermore, patients with OCD have a fairly good response to antidepressant clomipramine. Diagnostic and therapeutic strategies can conceivably be related on the examination of sleep patterns of psychiatric patients.

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Affective Disorders, PsychoticHumansSleep Wake DisordersSleep, REMJournal ArticleReview

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BibTeXRIS

R Rimon, M Fujita, N Takahata. 1986. Mood alterations and sleep.. https://doi.org/10.1111/j.1440-1819.1986.tb03137.x

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