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PubMed · 3557723

Relative deconvolution. An explicit method for bioavailability comparison not requiring intravenous administration.

P Veng-Pedersen·R Miller
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Abstract

A method is presented which enables an explicit evaluation of the relative rate and extent of drug absorption of drug products using an oral drug solution as a reference, thereby avoiding the need for intravenous administration of the drug. The method is demonstrated using data from two sustained release phenylpropanolamine preparations and an oral solution of this drug in a human subject.

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AbsorptionAdministration, OralAdultBiological AvailabilityDelayed-Action PreparationsHumansKineticsMalePhenylpropanolamineComparative StudyJournal ArticleResearch Support, Non-U.S. Gov't

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BibTeXRIS

P Veng-Pedersen, R Miller. 1987. Relative deconvolution. An explicit method for bioavailability comparison not requiring intravenous administration.. https://pubmed.ncbi.nlm.nih.gov/3557723/

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