PubMed HealthSearch

PubMed · 3580686

Pemphigus.

Abstract

Pemphigus is an autoimmune blistering disorder. Paradoxically intact blisters are rarely seen as the superficial blister is so fragile. The disease is frequently fatal if untreated. Pemphigus is an ideal model for autoimmunity as the antigen has been characterized and the antibody demonstrated to be pathogenic.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

J H Barth, V A Venning. 1987. Pemphigus.. https://pubmed.ncbi.nlm.nih.gov/3580686/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Steroid therapy.

Explore the source record for details and available documents.

Adrenal Cortex Hormones

[An outbreak of mostly extrapulmonary tuberculosis in a family practice].

An outbreak of mainly extrapulmonary tuberculosis (TB) in a group of about 550 patients with rheumatoid arthritis (RA) is described. These patients had been attending the practice of a former general practitioner who treated cases of rheumatoid arthritis with phenylbutazone and steroids. The number of diagnosed TB cases was 55. Six cases had a contagious lung localisation. The possible sources of the outbreak were analysed. Both a visit on a same day as a sputum positive patient (chi 2-trend: 20.4; p < 0.001) and the administration of steroids (odds ratio (OR): 36.2; 95% confidence interval (CI): 8.8-313) were independent risk factors. There also appeared to be a relationship between TB and RA (OR: 4.4; 95%-BI: 2.2-9.1). Exogenous re(infection) and endogenous reactivation are possible causes of this outbreak.

Adrenal Cortex Hormones