Acute selenium toxicosis in sheep.

D J Blodgett; R F Bevill

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PubMed · 3604043

Acute selenium toxicosis in sheep.

D J Blodgett·R F Bevill

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Abstract

Acute selenium (Se) toxicosis was evaluated in 20 female crossbred sheep, 8 to 14 mo of age. Five groups of 4 sheep each were given 0.4, 0.6, 0.7, 0.8, or 1.0 mg Se/kg body weight IM. The LD50 for sodium selenite was 0.7 mg Se/kg body weight with a standard error of 0.035 over a 192 hr observation period. The most evident clinical signs were dyspnea and depression. At necropsy, the most consistent lesions in animals which received 0.7, 0.8, and 1.0 mg Se/kg body weight were edematous lungs and pale mottled hearts. Highest tissue Se concentrations in declining order were found in the liver, kidney and heart.

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Animals Female Kinetics Lethal Dose 50 Selenium Sheep Sheep Diseases Tissue Distribution Journal Article

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D J Blodgett, R F Bevill. 1987. Acute selenium toxicosis in sheep.. https://pubmed.ncbi.nlm.nih.gov/3604043/

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